Litinas Konstantinos

 Year/Place of Birth: May 1955/ Rethymnon, Crete, Greece.

Family Status: Married, with a daughter and a son.

Undergraduate studies: 1973-1978, Chemistry Department, School of Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece. Bachelor in Chemistry.

Postgraduate studies: 1978-1984, Laboratory of Organic Chemistry, Chemistry Department, School of Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece (supervisor Prof. D. N. Nicolaides). “Studies on reactions of o-quinones with phosphonium ylides” (PhD).

Postdoctoral studies: 1992-1993, California Institute of Technology, Caltech, Pasadena, California, USA (Research in Olefin Metathesis, supervisor Prof. R. H. Grubbs, Nobel Laureate in Chemistry, 2005).

Fellowships: 1978-1981, Fellowship from National Fellowship Foundation (I.K.Y.) for PhD studies in Greece.

Academic Career: Laboratory of Organic Chemistry, Chemistry Department, School of Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece
                                1981-1986: Scientific Fellow
                                1986-1991: Lecturer
                                1991-1999: Assistant Professor
                                1999-2013: Associate Professor.
                                2013-now: Professor

Teaching

• Organic Chemistry
• Organometallic Chemistry & Catalysis

Research

• Οrganic Synthesis
• Natural Products Synthesis
• Synthesis of compounds with possible biological activity
• Synthesis of modified N-homonucleosides
• Application of organometallic reagents in Organic Synthesis
• Applications of metal-nanoparticles in Organic Synthesis

Synthesis of Coumarin derivatives

Synthesis of coumarin derivatives with possible biological activity. Some of them are natural products. The synthesis of the above derivatives has been achieved by Wittig reactions, reactions of nitriloxides, Diels-Alder reactions, Ring Closing Olefin Metathesis reactions (RCM), Cross Metathesis (CM) reactions, reactions catalyzed by Pd (II) or Gold- or Silver- Nanoparticles etc. Some of the above derivatives are studied (in collaboration with other Laboratories) for their biological activities as anti-inflammatories, antioxidants, antithrombotic or against Alzheimer’s disease.

Synthesis of Purine derivatives

Synthesis of purine derivatives and hybrids containing purine moieties. 1,3-Dipolar cycloaddition reactions as well as RCM and CM reactions are utilized for these syntheses.