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 Sarli Vasiliki, Assist. Professor
Laboratory: Organic Chemistry
 
 
 
ARISTOTLE
UNIVERSITY OF THESSALONIKI
DEPARTMENT OF CHEMISTRY
54124, THESSALONIKI
PHONE:+30 2310 997840
sarli@chem.auth.gr
 
 
 
Research Areas

The research interests of the Sarli lab lie in the fields of organic chemistry and chemical biology. Many new biological and medicinal advances were facilitated by probing biological systems at the molecular level using chemical tools. In particular, our laboratory is focused on the design and synthesis of small molecules and natural products as modulators of clinically relevant proteins for the study of biological processes and the development of novel therapeutics.

 
 Selected Publications
1. Sigala I, Ganidis G, Thysiadis S, Zografos AL, Giannakouros T, Sarli V, Nikolakaki E. 
"Lynamicin D an antimicrobial natural product affects splicing by inducing the expression of SR protein kinase 1. ", Bioorg Med Chem, 25(5), 1622-1629, (2017)
2. Trafalis D, Geromichalou E, Dalezis P, Nikoleousakos N, Sarli V 
"Synthesis and evaluation of new steroidal lactam conjugates with aniline mustards as potential antileukemic therapeutics.", Steroids, 115, 1-8, (2016)
3. Mpousis S, Thysiadis S, Avramidis N, Katsamakas S, Efthimiopoulos S, Sarli V 
"Synthesis and evaluation of gallocyanine dyes as potential agents for the treatment of Alzheimer's disease and related neurodegenerative tauopathies.", Eur J Med Chem, 108, 28-38, (2016)
4. M Grammatikopoulou, S Thysiadis, V Sarli 
"Gold-catalyzed spiro-N,O-ketal synthesis", Org Biom Chem, 13 (4, 1169-1178, (2015)
5. S Mpousis, S Thysiadis, N Avramidis, S Katsamakas, S Efthimiopoulos, V Sarli 
"Synthesis and evaluation of gallocyanine dyes as potential agents for the treatment of Alzheimer's disease and related neurodegenerative tauopathies",  Eur J Med Chem, 108,  28-38, (2015)
6. Chatzimpaloglou A, Kolosov M, Eckols TK, Tweardy DJ, Sarli V 
"Synthetic and biological studies of phaeosphaerides ", J Org Chem, 79(9), 4043, (2014)
7. A Chatzimpaloglou, MP Yavropoulou, KE Rooij, R Biedermann, U Mueller, S Kaskel, V Sarli 
"Total synthesis and biological activity of the proposed structure of phaeosphaeride a", J Org Chem, 77, 9659-67, (2012)
 
 
 
 Books
1. Kinesin motor inhibitors as effective anti-cancer drugs in the book Checkpoint Responses and Cancer Therapy, part of the series Cancer Drug Discovery and Development from The Humana Press, Inc; USA,
V. Sarli, A. Giannis, Pages:207 (2008)
2. Heterocyclic Chemistry At A Glance-John A. Joule, Keith Mills
Translation in Greek, V. Sarli, Pages:1-164 (2011)
 
   
  School of Chemistry
Aristotle University of Thessaloniki